Categories
Xanthoangelol
- CAS: 62949-76-2
- Purity: 99%
- Manufacturers supply cost-effective and customizable Xanthoangelol 62949-76-2
Manufacturers supply cost-effective and customizable Xanthoangelol 62949-76-2
- Molecular Formula: C25H28O4
- Molecular Weight: 392.495
- Vapor Pressure: 2.85E-15mmHg at 25°C
- Melting Point: 141-143 °C
- Boiling Point: 605.8°C at 760 mmHg
- PKA: 7.57±0.50(Predicted)
- Flash Point: 334.2°C
- PSA： 77.76000
- Density: 1.165g/cm3
- LogP: 5.93470
Xanthoangelol(Cas 62949-76-2) Usage
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General Description |
Xanthoangelol is a geranylated chalcone natural product belonging to the flavonoid subclass, known for its diverse biological and pharmacological activities. It is structurally characterized as 3-geranyl-2,4,4'-trihydroxychalcone or 2',4,4'-trihydroxy-3'-geranylchalcone. Xanthoangelol was synthesized efficiently in this study using regiospecific iodination and Suzuki coupling reactions, demonstrating improved yield and regiochemical control compared to previous methods. |
InChI:InChI=1/C25H28O4/c1-17(2)5-4-6-18(3)7-13-21-24(28)16-14-22(25(21)29)23(27)15-10-19-8-11-20(26)12-9-19/h5,7-12,14-16,26,28-29H,4,6,13H2,1-3H3/b15-10+,18-7+
62949-76-2 Relevant articles
Synthesis and anti-cancer activity evaluation of novel prenylated and geranylated chalcone natural products and their analogs
Wang, Hao-Meng,Zhang, Li,Liu, Jiang,Yang, Zhao-Liang,Zhao, Hong-Ye,Yang, Yao,Shen, Di,Lu, Kui,Fan, Zhen-Chuan,Yao, Qing-Wei,Zhang, Yong-Min,Teng, Yu-Ou,Peng, Yu
, p. 439 - 448 (2015/03/05)
Four natural chalcones bearing prenyl or...
Concise synthesis of prenylated and geranylated chalcone natural products by regiospecific iodination and Suzuki coupling reactions
Wang, Haomeng,Yan, Zhihong,Lei, Yanan,Sheng, Kai,Yao, Qingwei,Lu, Kui,Yu, Peng
supporting information, p. 897 - 899 (2015/03/03)
Four natural chalcones bearing prenyl or...
Concise synthesis of prenylated and geranylated chalcone natural products by regiospecific iodination and Suzuki coupling reactions
Wang, Haomeng,Yan, Zhihong,Lei, Yanan,Sheng, Kai,Yao, Qingwei,Lu, Kui,Yu, Peng
supporting information, p. 897 - 899 (2014/02/14)
Four natural chalcones bearing prenyl or...
Synthesis and antibacterial activity of chalcones bearing prenyl or geranyl groups from Angelica keiskei
Sugamoto, Kazuhiro,Matsusita, Yoh-Ichi,Matsui, Kana,Kurogi, Chiaki,Matsui, Takanao
experimental part, p. 5346 - 5359 (2011/08/04)
Chalcones bearing prenyl or geranyl grou...
62949-76-2 Process route
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1544322-63-5
(E)-1-(3-((E)-3,7-dimethylocta-2,6-dien-1-yl)-2,4-bis(methoxymethoxy)phenyl)-3-(4-(methoxymethoxy)phenyl)prop-2-en-1-one
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62949-76-2
xanthoangelol
| Conditions | Yield |
|---|---|
|
With
hydrogenchloride;
In
methanol; water;
at 0 - 50 ℃;
Inert atmosphere;
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72%
|
|
With
hydrogenchloride; methanol;
In
water;
for 6h;
Inert atmosphere;
|
54 mg
|
|
With
hydrogenchloride;
In
methanol;
for 6h;
Inert atmosphere;
|
54 mg
|
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-
1314539-28-0
4,4'-bis(methoxymethoxy)-3'-geranyl-2'-hydroxychalcone
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-
62949-76-2
xanthoangelol
| Conditions | Yield |
|---|---|
|
With
carbon tetrabromide;
In
isopropyl alcohol;
for 5h;
Reflux;
|
77%
|
62949-76-2 Upstream products
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1229515-77-8
(2E)-1-[3-geranyl-2-hydroxy-4-(methoxymethoxy)phenyl]-3-{4-{[2-(trimethylsilyl)ethoxy]methoxy}-phenyl}prop-2-en-1-one
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89-84-9
2',4'-dihydroxy-4-acetophenone
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1314539-21-3
2'-gerenyloxy-4'-(methoxymethoxy)acetophenone
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1314539-25-7
4,4'-bis(methoxymethoxy)-2'-geranyloxychalcone
62949-76-2 Downstream products
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74174-28-0
(2E)-1-[5-hydroxy-2-methyl-2-(4-methylpent-3-en-1-yl)-2H-1-benzopyran-6-yl]-3-(4-hydroxyphenyl)prop-2-en-1-one
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791113-09-2
4,2',4'-triacetoxy-3'-geranylchalcone
