Pharmaceutical

2-(3-Aminopropylamino)ethylsulfanylphosphonic acid trihydrate

  • CAS: 112901-68-5
  • Purity: 99%
  • Chinese Manufacturer Supply 2-(3-Aminopropylamino)ethylsulfanylphosphonic acid trihydrate 112901-68-5 On Stock with Competitive Price
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Quality products?make an important contribution to long-term revenue and profitability. Chinese Manufacturer Supply 2-(3-Aminopropylamino)ethylsulfanylphosphonic acid trihydrate 112901-68-5 On Stock with Competitive Price

1.What is the 2-(3-Aminopropylamino)ethylsulfanylphosphonic acid trihydrate ?

Amifostine may provide renal protection during PRRT using somatostatin analogs by mitigating radiation damage and reducing the absorbed kidney radiation dose. Amifostine remediates the degenerative effects of radiation on the mineralization capacity of the murine mandible.

amifostine trihydrate
112901-68-5

amifostine trihydrate

amifostine monohydrate
112901-68-5

amifostine monohydrate

Conditions
Conditions Yield
With ion exchange resin; pyrographite; In methanol; water; at -2 - 35 ℃;
dibromohydrate du N-(bromoethyl-2)diamino-1,3 propane
23545-42-8

dibromohydrate du N-(bromoethyl-2)diamino-1,3 propane

amifostine monohydrate
63717-27-1,112901-68-5

amifostine monohydrate

Conditions
Conditions Yield
With water; trisodium thiophosphate; N,N-dimethyl-formamide; at 15 ℃; for 1.5h;

2.What is the CAS number for 2-(3-Aminopropylamino)ethylsulfanylphosphonic acid trihydrate ?

The CAS number of 2-(3-Aminopropylamino)ethylsulfanylphosphonic acid trihydrate is 112901-68-5.

More information of 2-(3-Aminopropylamino)ethylsulfanylphosphonic acid trihydrate 112901-68-5 are:

CAS?Number

112901-68-5

Density

1.367g/cm3

Boiling Point

441.7 °C at 760 mmHg

Flash Point

220.9 °C

Vapor Pressure

4.9E-09mmHg at 25°C

HS CODE

2930909165

PSA

158.38000

LogP

0.64900

Pka

pKa1 <2.0; pKa2 4.2; pKa3 9.0; pKa4 11.7(at 25℃)

3.What are another words for 2-(3-Aminopropylamino)ethylsulfanylphosphonic acid trihydrate ?

Synonyms?for?2-(3-Aminopropylamino)ethylsulfanylphosphonic acid trihydrate 112901-68-5:Anifostine trihydrate;Ethanethiol,2-[(3-aminopropyl)amino]-, dihydrogen phosphate (ester), trihydrate (9CI);

4.What is the molecular formula of 2-(3-Aminopropylamino)ethylsulfanylphosphonic acid trihydrate?

The chemical formula of ?2-(3-Aminopropylamino)ethylsulfanylphosphonic acid trihydrate is?C5 H15 N2 O3 PS*H2 O which containing 5 Carbon atoms,17 Hydrogen atoms,2 Nitrogen atoms,4 Oxygen atoms and 1 Phosphorus atoms,and the molecular weight of??2-(3-Aminopropylamino)ethylsulfanylphosphonic acid trihydrate?is 232.241.

5.What is 2-(3-Aminopropylamino)ethylsulfanylphosphonic acid trihydrate (112901-68-5) used for?

Amifostine is a broad-spectrum cytoprotective agent, once used as a military anti-radiation agent, and now used as a protective drug for radiotherapy and chemotherapy. It has significantly effective in reducing the side effects of anticancer drugs such as cyclophosphamide, ciplatin, doxorubicin, and anti-HIV drugs such as 3-azido-3-deoxythymidine, without affecting the efficacy of anticancer or anti-HIV drugs curative effect. At present, the commercially available amifostine products include freeze-dried powder injection(ETHYOL )produced by American Life Sciences Co., Ltd. It is only available as a lyophilized powder for injection, but is thermally unstable.

InChI:InChI=1/C5H15N2O3PS.3H2O/c6-2-1-3-7-4-5-12-11(8,9)10;;;/h7H,1-6H2,(H2,8,9,10);3*1H2

Relevant articles related to 2-(3-Aminopropylamino)ethylsulfanylphosphonic acid trihydrate:

Article

Source

NOVEL DIHYDRATE FORM OF AMIFOSTINE AND PROCESS FOR ITS PREPARATION

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Page/Page column 16; 17; 18, (2008/06/13)

6.Buy 2-(3-Aminopropylamino)ethylsulfanylphosphonic acid trihydrate with the best price .

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