Categories
JTC 801
- CAS: 244218-51-7
- Purity: 99%
- Quality Factory Sells Top Purity 99% JTC 801 244218-51-7 with Safe Delivery
Quality Factory Sells Top Purity 99% JTC 801 244218-51-7 with Safe Delivery
- Molecular Formula: C26H25N3O2*ClH
- Molecular Weight: 447.964
- Vapor Pressure: 1.73E-13mmHg at 25°C
- Melting Point: 235℃
- Boiling Point: 580.9°Cat760mmHg
- Flash Point: 305.1°C
- PSA： 77.24000
- Density: g/cm3
- LogP: 6.97530
JTC 801(Cas 244218-51-7) Usage
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Biological Activity |
High affinity, selective NOP receptor antagonist (K i = 8.2 nM). Displays approximately 12.5-, 129- and 1055-fold selectivity over human μ -, κ - and δ -opioid receptors respectively. In vivo shows anti-nociceptive effects in acute pain models. Orally active. |
InChI:InChI=1/C26H25N3O2.ClH/c1-3-18-8-11-21(12-9-18)31-16-19-6-4-5-7-22(19)26(30)29-20-10-13-25-23(15-20)24(27)14-17(2)28-25;/h4-15H,3,16H2,1-2H3,(H2,27,28)(H,29,30);1H
244218-51-7 Relevant articles
FILAGGRIN PRODUCTION PROMOTER, THERAPEUTIC AGENT FOR DISEASES ASSOCIATED WITH REDUCTION IN PRODUCTION OF FILAGGRIN, AND METHOD FOR SCREENING FOR SAID THERAPEUTIC AGENT
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Page/Page column, (2015/06/16)
The present invention provides a highly ...
Amide derivatives and nociceptin antagonists
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, (2008/06/13)
The present invention relates to a compo...
244218-51-7 Process route
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244218-51-7
JTC 801
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59%
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