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amphotericin A

  • CAS: 1405-32-9
  • Purity: 99%
  • 99% Purity Commercial production amphotericin A 1405-32-9 with Cheapest Price
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99% Purity Commercial production amphotericin A 1405-32-9 with Cheapest Price We provide high quality amphotericin A (CAS 1405-32-9), at a very affordable prices to our customers.

1.What is the amphotericin A ?

Amphotericin A is a polyene macrolide antibiotic derived from Streptomyces bacteria, structurally related to the well-known antifungal drug amphotericin B. It demonstrates broad-spectrum antifungal activity against a variety of fungal infections by binding to ergosterol in fungal cell membranes, disrupting cell integrity, and causing cell death. Despite its high toxicity and the existence of safer alternatives, it remains a significant interest in the development of new antifungal drugs.

Used in Pharmaceutical Industry:
Amphotericin A is used as a research compound for the development of new antifungal drugs due to its broad-spectrum antifungal activity and unique mechanism of action.
Used in Clinical Practice:
Although not commonly used due to its high toxicity, amphotericin A is used as a last-resort treatment for severe fungal infections that are resistant to other antifungal agents, particularly in immunocompromised patients.
Used in Drug Delivery Systems:
Research is ongoing to develop novel drug delivery systems for amphotericin A to improve its safety profile, bioavailability, and therapeutic outcomes by encapsulating the drug in various carriers, such as liposomes or nanoparticles, to reduce its toxicity and enhance its efficacy against fungal infections.

2.What is the CAS number for amphotericin A ?

The CAS number of amphotericin A is 1405-32-9.

More information of amphotericin A 1405-32-9 are:

CAS?Number

1405-32-9

Density

1.33g/cm3

Boiling Point

1132.2°Cat760mmHg

Flash Point

638.5°C

Vapor Pressure

0mmHg at 25°C

Refractive Index

1.606

PSA

319.61000

LogP

1.63600

Pka

3.72±0.70(Predicted)

3.What is the molecular formula of amphotericin A ?

The chemical formula of?amphotericin A is C47H75 N O17 which containing 47 Carbon atoms,75 Hydrogen atoms,1 Nitrogen atoms and 17 Oxygen atoms,and the molecular weight, and the molecular weight of amphotericin A is 926.09

4.What is amphotericin A(1405-32-9)used for?

Amphotericin A is a polyene macrolide antibiotic derived from Streptomyces bacteria, structurally related to the well-known antifungal drug amphotericin B. It demonstrates broad-spectrum antifungal activity against a variety of fungal infections by binding to ergosterol in fungal cell membranes, disrupting cell integrity, and causing cell death. Despite its high toxicity and the existence of safer alternatives, it remains a significant interest in the development of new antifungal drugs.

InChI:InChI=1/C47H75NO17/c1-27-17-15-13-11-9-7-5-6-8-10-12-14-16-18-34(64-46-44(58)41(48)43(57)30(4)63-46)24-38-40(45(59)60)37(54)26-47(61,65-38)25-33(51)22-36(53)35(52)20-19-31(49)21-32(50)23-39(55)62-29(3)28(2)42(27)56/h5-6,8,10-18,27-38,40-44,46,49-54,56-58,61H,7,9,19-26,48H2,1-4H3,(H,59,60)/b6-5+,10-8-,13-11-,14-12+,17-15+,18-16+

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5.99% Purity Commercial production amphotericin A 1405-32-9 with Cheapest Price

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