Pharmaceutical

Almorexant

  • CAS: 871224-64-5
  • Purity: 99%
  • Factory Export Top Purity Almorexant 871224-64-5 In Stock
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What is the Almorexant ?

Almorexant is , while it's Molecular Formula is C29H31F3N2O3. Almorexant is a dual orexin receptor antagonist ACT-541468 used in the treatment of insomnia. It regulates sleep and wakefulness through two G protein-coupled receptors, namely Orexin 1 receptor and Orexin 2 receptor.

What is the CAS number for Almorexant ?

The CAS number of Almorexant is 871224-64-5.

More information of Almorexant 871224-64-5 are:

Synonyms

Almorexant;2-[(1S)-6,7-Dimethoxy-1-[2-[4-(trifluoromethyl)phenyl]ethyl]-3,4-dihydro-1H-isoquinolin-2-yl]-N-methyl-2-phenylacetamide;(2R)-2-((1S)-6,7-Dimethoxy-1-{2-(4-(trifluoromethyl)phenyl)ethyl}-3,4-dihydroisoquinolin-2(1H)-yl)-N-methyl-2-phenylacetamide;3,4-Dihydro-6,7-dimethoxy-N-methyl-alpha-phenyl-1-[2-[4-(trifluoromethyl)phenyl]ethyl]-2(1H)-isoquinolineacetamide;ACT-078573;

CAS?Number

871224-64-5

Molecular Formula

C29H31F3N2O3

Molecular Weight

512.572

Density

1.205 g/cm3

Boiling Point

620.4 °C at 760 mmHg

Flash Point

329 °C

PSA

50.80000

LogP

6.07070

Pka

15.04±0.46(Predicted)

What is Almorexant (871224-64-5) used for?

(R)-2-((R)-6,7-dimethoxy-1-(4-(trifluoromethyl)phenethyl)-3,4-dihydroisoquinolin-2(1H)-yl)-N-methyl-2-phenylacetamide is a complex organic compound with a unique molecular structure. It is characterized by its chiral centers, which give it specific stereochemistry and potential biological activity. (R)-2-((R)-6,7-dimethoxy-1-(4-(trifluoromethyl)phenethyl)-3,4-dihydroisoquinolin-2(1H)-yl)-N-methyl-2-phenylacetamide is a derivative of the isoquinoline class of alkaloids, which are known for their diverse range of pharmacological properties.

Articles related to Almorexant:

Article

Source

Stereoselective total synthesis of almorexant

Reddy, N. Siva Senkar,Reddy, B.V. Subba

supporting information, p. 3157 - 3159 (2014/05/20)

PROCESS FOR THE PREPARATION OF AN ENANTIOMERIC TRISUBSTITUTED 3,4-DIHYDRO-ISOQUINOLINE DERIVATIVE

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Page/Page column 7; 13; 14, (2010/12/29)

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