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Cefuroxime
- CAS: 55268-75-2
- Purity: 99%
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1.What is the Cefuroxime ?
Antibacterial.
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1189-71-5
isocyanate de chlorosulfonyle
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![(6R,7R)-7-[2-(2-furyl)-2-(methoxyimino)acetamido]-3-hydroxymethyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid](/upload/2026/8/f206ab9c82f64cda8144de13b7049c9e_31153d37-1557-4ecf-b103-05d4ae886482.png)
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56271-94-4
(6R,7R)-7-[2-(2-furyl)-2-(methoxyimino)acetamido]-3-hydroxymethyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
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-
55268-75-2
Cefuroxime
| Conditions | Yield |
|---|---|
|
isocyanate de chlorosulfonyle; (6R,7R)-7-[2-(2-furyl)-2-(methoxyimino)acetamido]-3-hydroxymethyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;
In
dimethylcarbonate;
at 0 - 5 ℃;
With
hydrogenchloride; water;
In
dimethylcarbonate;
at 10 - 15 ℃;
Product distribution / selectivity;
|
95% |
|
In
Methyl formate;
at -35 - -20 ℃;
Solvent;
Temperature;
Green chemistry;
|
93.3% |
|
isocyanate de chlorosulfonyle; (6R,7R)-7-[2-(2-furyl)-2-(methoxyimino)acetamido]-3-hydroxymethyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;
In
diethylcarbonate;
at 0 - 5 ℃;
for 0.5h;
With
hydrogenchloride; water;
In
diethylcarbonate;
at 10 - 15 ℃;
for 1.5h;
Product distribution / selectivity;
|
90% |
|
In
tetrahydrofuran; water;
at -70 - 5 ℃;
for 0.666667h;
Inert atmosphere;
|
70.5% |
|
In
tetrahydrofuran;
at -50 ℃;
for 1h;
|
-
-
cefuroxime sodium
-
-
55268-75-2
Cefuroxime
| Conditions | Yield |
|---|---|
|
With
hydrogenchloride;
In
water; acetone;
pH=2;
|
68.3% |
2.What is the CAS number for Cefuroxime ?
The CAS number of Cefuroxime is 55268-75-2.
More information of Cefuroxime 55268-75-2 are:
|
CAS?Number |
55268-75-2 |
|
Density |
1.76 g/cm3 |
|
Melting Point |
171.5-173 °C |
|
Refractive Index |
1.6000 (estimate) |
|
PSA |
199.06000 |
|
LogP |
0.49310 |
|
Pka |
pKa 2.5(H2O) (Uncertain) |
3.What are another words for Cefuroxime ?
Synonyms?for?Cefuroxime 55268-75-2:Cefaloxime;Cefasyn;Cefuroxim;Cefuroxime acid;Ketocef;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,3-[[(aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-furanyl(methoxyimino)acetyl]amino]-8-oxo-,(6R,7R)- (9CI);5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,3-[[(aminocarbonyl)oxy]methyl]-7-[[2-furanyl(methoxyimino)acetyl]amino]-8-oxo-,[6R-[6a,7b(Z)]]-;Biofuroksym;Biofuroxim;
4.What is the molecular formula of Cefuroxime?
The chemical formula of ?Cefuroxime is?C16H16N4O8S which containing 16 Carbon atoms,16 Hydrogen atoms,4 Nitrogen atoms,8 Oxygen atoms and 1 Sulfur atoms,and the molecular weight of??Cefuroxime?is 424.391.
5.What is Cefuroxime (55268-75-2) used for?
Cefuroxime axetil is the acetoxyethyl ester and oral prodrug of cefuroxime, a second-generation cephalosporin. It has a broad spectrum of action and is resistant to most P-lactamases. Cefuroxime axed is indicated for serious bacterial infections, especially where no identification of organism(s) has been made.
InChI:InChI=1/C20H22N4O10S/c1-9(25)33-10(2)34-19(28)15-11(7-32-20(21)29)8-35-18-14(17(27)24(15)18)22-16(26)13(23-30-3)12-5-4-6-31-12/h4-6,10,14,18H,7-8H2,1-3H3,(H2,21,29)(H,22,26)/b23-13-/t10?,14-,18-/m1/s1
Relevant articles related to Cefuroxime:
|
Article |
Source |
|
Preparation method of cefuroxime acid |
- Paragraph 0055; 0058-0059; 0060; 0065-0066; 0067; 0072-0073, (2021/04/21) |
|
Cefuroxime sodium compound prepared through advanced on-line process control technology and preparation thereof |
- Paragraph 0040; 0050; 0063; 0078, (2017/02/28) |
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